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Overview

Rhianne Curley

PhD Researcher

Rhianne joined the Centre for Doctoral Training (CDT) in September 2020.

Rhianne’s project title under the supervision of Prof Tia Keyes is: Precision targeted tumor responsive fluorophores: theranostic probes for real time biomarker sensing and for intraoperative fluorescence guided surgery.    The long-term aim of this project is to develop and optimise luminescent probes that can be used to selectively target cancer cells. These probes will have an application in both light-guided surgery and also in photonics.

Whilst studying her BSc in Biotechnology she completed a 9 month integrated training placement in Bristol-Myers Squibb, Cruiserath, as a member of the manufacturing science and technology upstream team. This opportunity allowed her to experience first-hand the benefits of industry placements for both enhancing lab based skills and also for personal development.

The option to gain industry experience while completing her PhD made the PIADS programme an extremely unique and attractive opportunity.

 

 

 

 

Biography

Rhianne joined the CDT in September 2020. Prior to that she completed a BSc in Biotechnology at Dublin City University. While studying for her Bachelors degree she had the opportunity to complete a 9 month integrated training placement in Bristol-Myers Squibb, Cruiserath, as a member of the manufacturing science and technology upstream team. This opportunity allowed her to experience first-hand the benefits of industry placements for both enhancing lab based skills and also for personal development. The option to gain industry experience while completing her PhD made the PIADS programme an extremely unique and attractive opportunity.

CDT PhD Project:
Project title: Precision targeted tumor responsive fluorophores: theranostic probes for real time biomarker sensing and for intraoperative fluorescence guided surgery.

Supervisor: Professor Tia Keyes, Dublin City University

Project Description: The long-term aim of this project is to develop and optimise luminescent probes that can be used to selectively target cancer cells. These probes will have an application in both light-guided surgery and also in photonics.

Rhianne’s main area of focus at the moment is the photophysical characterisation of Ruthenium probes and the use of these probes for imaging and measuring oxygen in cells using microscopy techniques such as Fluorescence-lifetime imaging microscopy, confocal miscroscopy and super-resolution stimulated emission depletion (STED) microscopy.

In selecting this PhD project she was motivated by a desire to strengthen her knowledge and enhance her skills in biophotonics and imaging. She has a keen interest in immune-oncology with which this project is closely aligned.

Aside from this, she enjoys travelling, yoga and hiking.